Biomarkers in Overactive Bladder: A New Objective and Noninvasive Tool?

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Biomarkers in Overactive Bladder: A New Objective and Noninvasive Tool?

Overactive bladder syndrome (OAB) is a highly prevalent urinary dysfunction, with considerable economic and human costs. Clinical diagnosis of OAB is still based on subjective symptoms. A new accurate, objective and noninvasive test to diagnose OAB and assess therapeutic outcome is lacking. Recent studies in lower urinary tract (LUT) dysfunctions, particularly in OAB patients, indicate that uri...

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Biomarkers in the Overactive Bladder Syndrome

Overactive bladder (OAB) is a symptomatic complex affecting both men and women. The overall incidence is above 10% but may exceed 40% in the elderly population (Irwin et al., 2006; Irwin et al., 2009; Sexton et al., 2009a). OAB is defined by the International Continence Society (ICS) as a clinical syndrome characterized by urinary urgency, with or without incontinence, usually with frequency an...

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Symptom assessment tool for overactive bladder syndrome--overactive bladder symptom score.

OBJECTIVES Overactive bladder (OAB) is a common symptom syndrome with urgency, urinary frequency, and urgency incontinence. To collectively express OAB symptoms, we developed the overactive bladder symptom score (OABSS). METHODS Four symptoms--daytime frequency, nighttime frequency, urgency, and urgency incontinence--were scored. The weighing score was based on a secondary analysis of an epid...

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Biomarkers in overactive bladder : Where do we stand today ?

Whatever the concept one has of a biological marker, the ideal test to be used as a biomarker in OAB is yet to be identified. Nevertheless, it is easy to agree upon several features, which lacking, will downbeat the enthusiasm for the test. Required characteristics include: to be non-invasive, to be measured by a simple and reproducible method in easily collectable biological samples, to really...

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Overactive bladder.

Overactive bladder (OAB) is common and has a negative impact on a patient's quality of life. It is important for physicians to know how to identify and manage patients with this condition. Usually only basic clinical evaluations and a good patient history are necessary to diagnose OAB. Effective and safe oral therapy is available and can be initiated by primary care physicians.

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ژورنال

عنوان ژورنال: Advances in Urology

سال: 2011

ISSN: 1687-6369,1687-6377

DOI: 10.1155/2011/382431